Is Corneal Collagen Cross-Linking Beneficial as an Adjunct to the Conventional Treatment of Bacterial Keratitis?

Background: To evaluate the therapeutic effects of corneal collagen cross-linking CXL as an adjuvant to standard antimicrobial agents in treatment bacterial keratitis when compared with alone. Methods: This prospective comparative interventional study included 20 eyes patients clinical and laboratory evidence who attended Outpatient Cornea Unit, Ophthalmology Department, Faculty Medicine Assiut University Hospital, Assiut, between January 2019 December 2020.Patients were divided into two groups: group A, treated using Dresden Protocol at EL-Nour Eye Centre, B antibiotics Results: Group A had ten age range 20-80 years (mean 49.2 years), while that (ten patients) was 19 -70 47.3 years). The ulcer sizes started decrease significantly from week 2 3 B. epithelization time different groups reepithelization 60% cases two, it began three There no significant difference V/A after treatment. Conclusion: adjunct topical more effective treating than conventional therapy alone, led shorter recovery times due rapid healing, resolution infiltration, faster symptomatic relief patients. Despite promoted heal quickly, there change before or alone .